Správná výživa má pozitívny vplyv na imunitný systém

Gastrointestinálny trakt je komplexný a dynamický ekosystém obsahujúci rozmanité spektrum mikroorganizmov. Komplexné společenstvá mikroorganizmov, ktoré kolonizujú ľudský gastrointestinálny trakt zohrávajú dôležitú úlohu v ľudskom zdraví. Črevná mikrobiota se podieľa na metabolických, nutričných, fyziologických a imunologických procesoch v ľudskom tele.¹ 

70 % imunitného systému se nachádza v čreve^2,3, preto môžu podporovať imunitný systém konkrétne nutrienty. Patria medzi ne špecifické proteíny4, vitamíny a minerálne látky⁵, vláknina (rozpustná a nerozpustná)^6,7, pre-, pro-, post-, synbiotiká^8-12 a tuky¹³. Tieto nutrienty majú priamy vplyv na 4 interagujúce zložky imunitného systému – vrodenú i získanú imunitu, črevný mikrobióm a črevnú bariéru^14-16

Sondová výživa Nutrison s vlákninou MF6^TM obsahuje unikátnu zmes 6 druhov rozpustnej a nerozpustnej vlákniny pre podporu zdravia čreva a imunity. MF6^TM vláknina odráža vhodný pomer rôzných druhov vlákniny v strave.

MF6^TM vláknina – jej vplyv na podporu imunitného systému

Účinnost MF6^TM vlákniny bola preukázana v 11 vedeckých prácach^17-27. MF6^TM redukuje výskyt hnačiek, zlepšuje tranzitný čas, redukuje výskyt zápchy, redukuje nadúvanie, zvyšuje množstvo bifidobaktérií, zvyšuje produkciu mastných kyselín s krátkym reťazcom (SCFA), skracuje pobyt v nemocnici a znižuje počet komplikácií.

1 Gerritsen J, Smidt H, Rijkers GT, et al. Intestinal microbiota in human healthand disease: the impact of probiotics. Genes Nutr.2011; 6:209-240 2. West Ch, Renz H, Jenmalm M, et al. The gut microbiota and inflammatory noncommunicable diseases: Associations and potentials for gut microbiota therapies. J. Allergy Clin. Immunol. 2015 Jan; 135(1):3-13. 3. Jung C, Hugot JP, Barreau F. Peyer’s Patches: The Immune Sensors of the Intestine. Int J Inflam. 2010 Sep 19; 2010:823710. 4. Calder PC. Branched-chain amino acids and immunity. J Nutr. 2006 Jan; 136(1 Suppl):288S-93S. 5. Maggini S, Wintergerst E, Beveridge S, et al. Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. Br J Nutr. 2007 Oct; 98 Suppl 1:S29-35. 6. Schley PD, Field CJ. The immune-enhancing effects of dietary fibres 
and prebiotics. Br J Nutr. 2002 May; 87 Suppl 2:S221-230. 7. Valdes AM, Walter J, Segal E, et al. Role of the gut microbiota in nutrition and health. BMJ. 2018 Jun 13; 361:k2179 8. Druart C, Alligier M, Salazar N, et al. Modulation of the gut microbiota by nutrients with prebiotic and probiotic properties. Adv Nutr. 2014 Sep 15; 5(5):624S-633S. 9. Wopereis H, Oozeer R, Knipping K, et al. The first thousand days - intestinal microbiology of early life: establishing a symbiosis. Pediatr Allergy Immunol. 2014 Aug; 25(5):428-38. 10. Tsai Y, Lin T, Chang Ch, et al. Probiotics, prebiotics and amelioration of diseases. J Biomed Sci. 2019 Jan 4; 26(1):3. 11. Mantziari A, Salminen S, Szajewska H, et al. Postbiotics against Pathogens Commonly Involved in Pediatric Infectious Diseases. Microorganisms. 2020 Sep 30; 8(10):1510. 12. Hernández-Granados MJ, Franco-Robles E. Postbiotics in human health: Possible new functional ingredients? Food Res Int. 2020 Nov; 137:109660. 13. Troesch B, Eggersdorfer M, Laviano, A, et al. Expert Opinion on Benefits of Long-Chain Omega-3 Fatty Acids (DHA and EPA) in Aging and Clinical Nutrition. Nutrients. 2020 Aug 24;12(9):2555. 14. Paparo L, di Costanzo M, di Scala C, et al. The influence of early life nutrition on epigenetic regulatory mechanisms of the immune system. Nutrients. 2014; 6:4706–4719. 15. Zheng D, Liwinski T, Elinav E. Interaction between microbiota and immunity in health and disease. Cell Res. 2020 Jun; 30(6):492-506. 16. Valdes AM, Walter J, Segal E, et al. Role of the gut microbiota in nutrition and health. BMJ. 2018 Jun 13; 361:k2179. 17. Jakobsen LH, Wirth R, Smoliner C, et al. Gastrointestinal tolerance and plasma status of carotenoids, EPA and DHA with a fiber enriched tube feed in hospitalized patients initiated on tube nutrition: Randomized controlled trial. Clin Nutr. 2017 Apr; 36(2):380-388. 18. Yagmurdur H, Leblebici F. Enteral nutrition preference in critical care: fibre-enriched or fibre-free? Asia Pac J Clin Nutr. 2016; 25(4):740-6. 19. Wierdsma NJ, Kruizenga HM, Droop A, et al. Comparison of two tube feeding formulas enriched with guar gum or mixed dietary fibres - English translation. Ned Tijdschr Voeding Diet. 2001; 56(11):243-7. 20. Silk DBA, Walters ER, Duncan HD, et al. The effect of a polymeric enteral formula supplemented with a mixture of six fibres on normal human bowel function and colonic motility. Clin Nutr. 2001; 20(1):49-58. 21. Trier E, Wells JCK, Thomas AG. Effects of a multifibre supplemented paediatric enteral feed on gastrointestinal function. J Pediatr Gastroenterol Nutr. 1999; 27:595. 22. Hofman Z, van Drunen JDE, Brinkman JG, et al. Tolerance and efficacy of a multi-fibre enriched tube-feed in paediatric burn patients. Clin Nutr 2001; 20(3):63–64 (abstract). 23. Daly A, Johnson T, MacDonald A. Is fibre supplementation in paediatric sip feeds beneficial? J Hum Nutr Diet. 2004; 17:365–370. 24. Guimber D, Bourgois B, Beghin L, et al. Effect of multifibre mixture with prebiotic components on bifidobacteria and stool pH in tube-fed children. Br J Nutr. 2010; 104:1514–22. 25. Schneider SM, Girard-Pipau F, Anty R, et al. Effects of total enteral nutrition supplemented with a multi-fibre mix on faecal short-chain fatty acids and microbiota. Clin Nutr. 2006; 25:82-90. 26. Majid HA, Emery PW, Whelan K. Faecal microbiota and short-chain fatty acids in patients receiving enteral nutrition with standard or fructo-oligosaccharides and fibre-enriched formulas. Clin Nutr. 2001; 20(1):23–39. 27. Karakan T, Ergun M, Dogan I, et al. Comparison of early enteral nutrition in severe acute pancreatitis with prebiotic fiber supplementation versus standard enteral solution: A prospective randomized double-blind study. World J Gastroenterol. 2007; 13(19):2733-2737.

TUBE22ALLSPE10SK